Evaluation of protein quality: methodological considerations.

نویسنده

  • A E Bender
چکیده

It is 25 years since the Society held a meeting on this same topic (12 October 1957). The enormous efforts that have gone into protein evaluation in the intervening quarter century suggest a need to reiterate and emphasize points made at that meeting (Bender, 1958) namely, that all measures of protein quality are a function of the limiting amino acid (AA), that the tests do not yield any information about other AA and that there is no ‘true’ value with which to compare new methods. Protein efficiency ratio (PER) has been used for too long as the touchstone of protein quality evaluation and it is time to abandon it. The fundamental error underlying all this work is the attempt to express protein quality by a single figure. Such an attempt might have been justified when biological measures were first developed because at that time it was not known that the value was dependent on the AA in the food-in fact, the major methods were in use before the last of the essential AA, threonine, was discovered. The term NDpE is used in which both quality (actually the amount of (unspecified) limiting AA) and quantity are incorporated. NDpE does not indicate whether there is insufficient protein in the diet, whether more food of the same type would be beneficial or whether the quality of the protein is low and supplementation is the solution,

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Quality Assessment of Published Articles in Iranian Journals Related to Economic Evaluation in Health Care Programs Based on Drummond’s Checklist: A Narrative Review

AbstractHealth economic evaluation research plays an important role in selecting cost-effective interventions. The purpose of this study was to assess the quality of published articles in Iranian journals related to economic evaluation in health care programs based on Drummond’s checklist in terms of numbers, features, and quality. In the present review study, published articles (Persian and En...

متن کامل

Appraising the methodological quality of the clinical practice guideline for diabetes mellitus using the AGREE II instrument: a methodological evaluation

OBJECTIVES To evaluate the methodological quality of the Palestinian Clinical Practice Guideline for Diabetes Mellitus using the Translated Arabic Version of the AGREE II. DESIGN Methodological evaluation. A cross-cultural adaptation framework was followed to translate and develop a standardised Translated Arabic Version of the AGREE II. SETTING Palestinian Primary Healthcare Centres. PAR...

متن کامل

Guidelines for the Design and Conduct of Clinical Studies in Knee Articular Cartilage Repair

Objective: To summarize current clinical research practice and develop methodological standards for objective scientific evaluation of knee cartilage repair procedures and products. Design: A comprehensive literature review was performed of high-level original studies providing information relevant for the design of clinical studies on articular cartilage repair in the knee. Analysis of cartila...

متن کامل

Evaluation of the Quality of Cancer-Related Fatigue Clinical Practice Guidelines

Background: Improvement of the quality ofcancer-related fatigue clinical practice guidelines (CPGs) is an important issue in oncology. Aim: This study aimed to determine the methodological quality of CPGs about cancer-related fatigue management using the AGREE II instrument. Method: This study involved a systematic search, followed by a descriptive study, to evaluate the methodological quality ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The Proceedings of the Nutrition Society

دوره 41 3  شماره 

صفحات  -

تاریخ انتشار 1982